5a-hydroxy Laxogenin cas 56786-63-1 CAS NO.56786-63-1

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Product name: 5a-hydroxy laxogenin, 5 Alpha-Hydroxy-Laxogenin

Appearance: White Powder 
Molecular Formula: C27H42O5                                     
                                                                                                                     
Molecular Weight: 446.619

Cas No: 56786-63-1

Purity: 98%
Laxogenine as a new type Inhibit cancer promoter ,due to very less content in nature plant, we create a green bioconversion method to get a highly purified 5-Alpha-hydroxy-Laxogenin from nature plant materials. Meanwhile, we developed a new microencapsule 5-Alpha-hydroxy-Laxogenin, with very good bioavailability.

 

Product Name:	Polyethylene-polypropylene glycol
Synonyms:	BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL;SYNPERONIC F 108;SYNPERONIC L 121;SYNPERONIC L 122;SYNPERONIC P 105;SYNPERONIC P 85;SYNPERONIC PE(R)/F68;SYNPERONIC PE(R)/L61
CAS:	9003-11-6
MF:	C5H10O2
MW:	0
EINECS:	618-355-0

 

 

Product Name:	Lamivudine
Synonyms:	LaMivudine(Epivir);4-AMino-1-[(2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;3TC (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine;3TC/Epivir-HBV;4-AMino-1-((2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl)pyriMidin-2(1H)-one;LaMivudine-13C-d2;cis-Lamivudine;(-)-BCH-189
CAS:	134678-17-4
MF:	C8H11N3O3S
MW:	229.26
Product Categories:	API;DENDRID;Piperazines;Active Pharmaceutical Ingredients;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Anti-virals;Intermediates & Fine Chemicals;Pharmaceuticals;API's;HIV/AIDS/Related Products;Sulfur & Selenium Compounds
Mol File:	134678-17-4.mol

 

 

 

 

What is Kojic Acid

   Kojic acid is a chelation agent produced by several species of fungi, especially Aspergillus oryzae, which has the Japanese common name koji.Kojic acid is a by-product in the fermentation process of malting rice, for use in the manufacturing of sake, the Japanese rice wine. It is a mild inhibitor of the formation of pigment in plant and animal tissues, and is used in food and cosmetics to preserve or change colors of substances. It forms a bright red complex with ferric ions.

 

 

Applications:

 

♦.Kojic acid can reduces age spots and pigmentation on face and body, typically caused by sun damage. 
♦. It can eliminate free radicals, strengthen cell activity.
♦. Kojic acid is also known to have an anti-microbial effect.
♦. Non-toxic to person and livestock, pollution-free pesticide in insecticide production.

Product Name: Hyaluronic Acid 

 

Product Name:	Hyaluronic acid
Synonyms:	[BETA-SODIUM-GLUCONATE-(1,3)-BETA-N-ACETYL-D-GLUCOSAMINE-1,4-]N;COPOLY(BETA-GLUCURONIC ACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4] SODIUM SALT;HYALURONIC ACID NA-SALT;HYALURONIC ACID, SODIUM SALT, STREPTOCOCCUS SPECIES;HYALURONIC ACID SODIUM;HYALURONIC ACID HUMAN SODIUM SALT;POLY(BETA-GLUCURONIC ACID-[1->3]-BETA-N-ACETYLGLUCOSAMINE-[1->4]), ALTERNATING;SODIUM HYALURONATE (STREPTOCOCCUS)
CAS:	9004-61-9
MF:	C14H22NNaO11
MW:	403.31
EINECS:	232-678-0
Mol File:	9004-61-9.mol

 

 

 

 

What is Hyaluronic acid 

 

Hyaluronic acid(HA) is a straight chain macromolecular mucopolysaccharide composed Of repeat disaccharide units of glucuronic acid and N-acetylglucosamine. It widely consists in the extracellular space of human and animal tissue, vitreum, umbilical cord, skin joints synovia and cockscomb, etc. The commercial HA is commonly a sodium salt, called sodium hyaluronate, habitually called hyaluronic acid. HA is a new biological at home and abroad. Its molecular weight is from several ten thousand to several million. It's aqueous solution has outstanding moisture keeping ability, high viscoelasticity and lubricity. It is widely used in cosmetics, pharmacy and health and beauty food. 

 

 

Applications:

 

Biochemical drugs with high clinical value, which are widely used in all kinds of eye surgery, such as crystal implantation, corneal transplantation and glaucoma surgery, etc.Can also be used to treat arthritis and accelerate wound healing.Used in cosmetics, it can have unique skin protection effect, can keep skin moist and smooth, delicate, soft, elastic, has the anti-wrinkle, anti-wrinkle, beauty care and restore the skin physiology function.

 

1. Food Grade 
2. Cosmetic Grade 
3. Eyedrops Grade(Pharm Grade) 
4. Injection Grade(Pharm Grade) 
5. High molecular weight HA 
6. Low molecular weight HA

Product Name:Tetrahexyldecyl Ascorbate

 

Product Name:	ASCORBYL TETRA-2-HEXYLDECANOATE
Synonyms:	tetrahexyldecylascorbate;ASCORBYL TETRA-2-HEXYLDECANOATE;L-Ascorbic acid, tetrakis(2-hexyldecanoate);L-Ascorbic acid,2,3,5,6-tetrakis(2-hexyldecanoate);BV-OSC;Nikkol VC-IP;VC-IP;Vitamin C tetra-isopalmitate
CAS:	183476-82-6
MF:	C70H128O10
MW:	1129.76
EINECS:
Product Categories:
Mol File:	183476-82-6.mol

 

 

Specification example:

 

Item	Specifications	Results
Assay (Icariin) by HPLC	98%	≥99.9%
Appearance	White or light yellow crystalline or crystalline powder	White crystalline powder
character	water-soluble	Conformity with provisions
Odor	odorless	Conformity with provisions
specific rotation	+20.5°~21.5°	+20.1°
Ablaze burning scraps	≤0.1%	0.04%
Heavy metal	≤10mg/kg	<10mg/kg
As	≤3mg/kg	<3mg/kg
Pb	≤2mg/kg	<2mg/kg
Fe	≤2mg/kg	<2mg/kg
Cu	≤5mg/kg	<5mg/kg
Conclusion	The results conforms with GB 14754-2010 standards

 

 

CAS Number:638-94-8
Name:Desonide
Formula:C24H32O6
Molecular Weight:416.51
Synonyms:Prenacid;Desilux;Pregna-1,4-diene-3,20-dione,11,21- dihydroxy-16,17-[(1-methylethylidene)bis- (oxy)]-,(11a,16R)-;Topifug;Locapred;Tridesilon;Flusemidon;Hamiltoderm;Desonide [USAN:BAN:INN];Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (11beta,16alpha)-;Apolar;Otic Tridesilon;Steroderm;Prednisolone-16,17-acetonide, 16-alpha-hydroxy-;DesOwen;Tridesonit;Sterax;Desonidum [INN-Latin];Budesonide acetonide;
EINECS:211-351-6
Density:1.3 g/cm3
Boiling Point:580.1 °C at 760 mmHg
Flash Point:196.9 °C
Appearance:Powder

Application:

1. Can be absorbed through the skin antikeratinizing, stimulate the growth of collagen and elastin, increase the thickness of the epidermis and dermis. Enhance skin elasticity, eliminate wrinkles and promote skin renewal, keeping the skin vitality. For cream, moisturizing cream, Cream, shampoo, conditioner, etc.
2. Vitamin A acetate oil to maintain the body's normal metabolism, cell membrane to maintain stability and development, to maintain the normal function of the reproductive system, formation of the visual, ease keratinized tissue, enhance immunity cells have significant effects.

    Product Description

 

   Certification of Analysis

 

 

TEST ITEM		SPECIFICATION
Appearance		White or almost white crystalline powder
Identification		FT-IR
		HPLC
Water		3.0%
Melting Point		148°C­—158°C
Residue on Ignition		≤0.1%
Heavy metals		≤ 20ppm
Residual  Solvents	Acetone	≤ 5000ppm
	Dichloromethane	≤ 600ppm
	n-Hexane	≤ 290ppm
	Acetic acid	≤ 5000ppm
	Ethyl acetate	≤ 5000ppm
	Tetrahydrofuran	≤ 720ppm
	Ethanol	≤ 5000ppm
Related substances	cabazitaxel	≤ 0.3%
	10-DABIII	≤ 0.3%
	Any other single impurity	≤ 0.1%
	Total impurities	≤ 1.0%
Chromatographic purity(By HPLC)		≥99.0%

 

                          Function&Application

 

 

Cabazitaxel (previously XRP-6258) is a semi-synthetic derivative of a natural taxoid. It was developed by Sanofi-Aventis and was approved by the U.S. FDA for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.

Cabazitaxel in combination with prednisone is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment.

 

 Cabazitaxel anticancer mechanism and characteristics similar with docetaxel, belongs to anti-microtubule drugs. Cabazitaxel through binding to tubulin, promoting their assembly into microtubules, and can prevent these have assembled a microtubule disintegration of the stabilization of microtubules, thereby inhibiting cell mitosis, and interphase cellular functions (interphasecellularfunctions) of play.

    Product Description

   Certification of Analysis

 

 

Product Information
Product Name	Docetaxel Anhydrous
Molecular Formula	C43H53NO14 (807.88)
Cas No.	114977-28-5
Quality standard	complies with In-house Standard
Analysis	Standard
Assay(W/W)	93.0-102.0%
Purity(HPLC)	≥93.8%
Physical Control
Appearance	White crystalline powder
Identification	Conforms
Specific Optical Rotation	-40°~-47°
Water	≤3.0%
Chemical Control
Residue of solvents	Complies with ICH requirement
Residue on Ignition	NMT0.2%
Bacteria Endotoxins	0.4EU/MG
Heavy Metal	NMT20ppm
Chromatographic Impurities
Highest Individual Impurity	NMT0.1%
Unknown Impurity	NMT0.1%
Total Impurity	NMT0.5%
Microbiological Control
Total Aerobic Microbial Count	NMT 100cfu/g
S.Aureus & Aeruginosa	Negative
Salmonella & E.Coil	Negative
Storage
Store at 2-8°C, In well closed containers and protect from light and moisture

 

                          Function&Application

 

 

Function:

Pharmacological Function:

It is a kind of anticancer drugs. It has the curative effect on many kinds of cancers, extremely

on the ovarian cancer, breast cancer. Its cure rate reaches to 33%, effectiveness to 75%.

 

Application:

1.Medical Purpose:

a. Used to treat patients with lung, ovarian, breast advanced forms of Kaposi's sarcoma.

b. Used for the prevention of restenosis. 

2.Food Additive

3.Cosmetics

4.Forage Additive

 

Items	specification	results
appearance	fluffy white powder	standard
viscosity (20 r/min,25 ℃ ,mpa,s)	19000-35000	21000
solution clarity (420 nm,%)	40000-60000	55700
heavy metals (mg/kg)	AS <2	pass
heavy metals (mg/kg)	Pb+As+Hg+Sb <10	pass
packing density (g/100ml)	21.0-27.0	pass
loss and drying(%)	<2.0	pass
Residual Acrylic acid(%)	<0.25	0.16
Residual Benzene (%)	<0.50	0.4

 

Items	Specification
Appearance	White or almost white powder or   crystalline powder, odorless
Melting point	152~156℃
Specific rotation	-16.0°~ -19.0°
Identification	1) The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in assay.
	2) IR spectra is consistent with CRS.
pH	4.5~6.5
Chlorides	≤0.02%
Fluorides	≥4.8%
Related substances	Individual impurity    ≤0.5%       Total impurity        ≤2.0%
Loss on drying	≤0.5%
Residue on ignition	≤0.1%
Heavy metals	≤20ppm
Assay	≥98.0%

 

product Name	Hydroxyurea
Synonyms	Hydroxycarbamide; 1-hydroxyurea; Biosupressin; sq 1089; wr 83799; Carbamohydroxamic acid; Carbamohydroximic acid; Carbamoyl oxime; Carbamyl hydroxamate; Hidrix; Hidroxicarbamida; HU; Hydrea; Hydreia; Hydroxycarbamine; Hydroxylurea; hydroxy urea (d4); Hydura; Hydurea; Litaler; Litalir; N-(aminocarbonyl)hydroxylamine; N-Carbamoylhydroxylamine; N-Hydroxyurea; Onco-carbide; Oxyurea; sk 22591; Hydroxy urea; amino(oxido-λ5-azanyl)methanone
Molecular Formula	CH4N2O2
Molecular Weight	76.0547
InChI	InChI=1/CH4N2O2/c2-1(4)3-5/h3H2,(H2,2,4)
CAS Registry Number	127-07-1
EINECS	204-821-7
Water solubility	soluble
Density	1.733g/cm3
Melting point	142-146°C
Refractive index	1.543