China (Mainland)
17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate CAS NO.52-01-7
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,
- Product Details
Keywords
- 17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate
- 52-01-7
- 17-alpha-Pregn-4-ene-21-carboxylic acid,
Quick Details
- ProName: 17-Hydroxy-7-alpha-mercapto-3-oxo-17-a...
- CasNo: 52-01-7
- Molecular Formula: C24H32O4S
- Appearance: White to Off White Solid
- Application: diuretic, aldosterone antagonist
- DeliveryTime: 12days
- PackAge: in drums or customized
- Port: Tianjin xingang
- ProductionCapacity: 10 Metric Ton/Day
- Purity: 99%
- Transportation: by sea
- LimitNum: 1 Kilogram
- Heavy metal: less than 0.4%
- Grade: Industrial Grade
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Details
| 17-Hydroxy-7-alpha-mercapto-3-oxo-17-alpha-pregn-4-ene-21-carboxylic acid-gamma-lactone-7-acetate Chemical Properties |
| mp | 207-208 °C(lit.) |
| alpha | -37 º (c=1, CHCl3) |
| refractive index | -36 ° (C=1, CHCl3) |
| storage temp. | Store at RT |
| Water Solubility | practically insoluble |
| Merck | 8760 |
| CAS DataBase Reference | 52-01-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Spironolactone(52-01-7) |
| EPA Substance Registry System | Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy- 3-oxo-, .gamma.-lactone, (7.alpha.,17.alpha.)-(52-01-7) |
| Safety Information |
| Hazard Codes | T,Xn,Xi |
| Risk Statements | 60-40-36/37/38 |
| Safety Statements | 53-22-36/37/39-45-36-26 |
| WGK Germany | 3 |
| RTECS | TU4725000 |
| Hazardous Substances Data | 52-01-7(Hazardous Substances Data) |
| Category | toxic substances |
| Toxicity grading | highly toxic |
| Acute toxicity | intraperitoneal - rat LD50: 277 mg / kg; intraperitoneal port - Mouse LD50: 260 mg / kg |
| Flammability and hazardous characteristics | easily flammable with combustion generating toxic fumes of sulfur oxides |
| Storage characteristics | Treasury: ventilation, low-temperature and dry; store it separately from food raw materials |
| Extinguishing agent | Dry powder foam, sand, carbon dioxide, spray water |
| Chemical Properties | White to Off White Solid |
| Usage | It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia |
| Usage | diuretic, aldosterone antagonist |
| Biological Activity | Competitive mineralocorticoid (aldosterone) receptor antagonist that exhibits antihypertensive activity in vivo . Also displays antiandrogen activity and inhibits steroid hormone biosynthesis. |