Diclofenac sodium cas 15307-79-6 CAS NO.15307-79-6

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Product name: Diclofenac sodium

CAS:15307-79-6

MF:C14H10Cl2NNaO2

MW:318.13

Appearance:White  or slightly  crystalline powder

Assay:99%Min

Loss on drying:0.2 %

Heavy metals:Less than 10ppm

Package:25kg/drum

Application: Antibiotic and Antimicrobial Agents

Diclofenac Sodium is the salt form of diclofenac, an active metabolite of the NSAID aceclofenac (sc-217557). Hydrolysis of

 

aceclofenac, an inhibitor of interleukin-1B-induced prostaglandin E2 production with no inhibitory activity against Cox

 

(cyclooxygenase), generates diclofenac, an inhibitor of both Cox-1 and Cox-2. Oxidation of diclofenac produces the metabolite

 

4'-hydroxy diclofenac (sc-202423) which demonstrates specific inhibition of Cox-2. Inhibition of Cox by diclofenac and 4'-hydroxy

 

diclofenac suppresses prostaglandin E2 synthesis, producing antiinflammatory and analgesic effects. Diclofenac is also

 

shown to stabilize the native tetrameric conformation of transthyretin (TTR) fibrils, preventing the formation of insoluble

 

amyloidogenic TTR deposits. Diclofenac Sodium is a substrate of CYP2C9.

 

  

Items	Specifications
Appearance	powder
Purity (gc area %)	≥ 98.0%
H NMR	Conforms to structure

    Product Description

   Certification of Analysis

 

 

Items	Index
Appearance	Colorless to light yellow transparent liquid
Solid content %	30.0 min	50.0 min	62.0-64.0
Free monomer (as AA) %	0.50 max	0.50 max	1.0 max
Density (20℃) g/cm3	1.10 min	1.20 min	1.20 min
pH(1% water  solution)	2.5-4.5	2.5-4.5	2.0-3.0

 

                          Function&Application

 

 PAA can be used as scale inhibitor and dispersant in circulating cool water systems in power plants, iron & steel factories, chemical fertilizer plants, refineries and air conditioning systems. Dosage should be in accordance with water quality and equipment materials. When used alone, 1-15mg/L is preferred.

 

    Product Description

English name:2-Chloro-5-nitrobenzoic acid  

Synonyms:5-nitro-2-chlorobenzoic acid; 2-chloro-5-nitrobenzoate  

Molecular Formula:C7H3ClNO4  

Molecular Weight:200.5566  

CAS Registry Number:2516-96-3  

EINECS:219-739-7  

Melting point:164-168°C

Boiling point:356.5°C at 760 mmHg

Flash point:169.4°C

Vapour Pressur:1.06E-05mmHg at 25°C  

Synonyms : RARECHEM AL BO 0234;2-CHLORO-5-NITROBENZOIC ACID;5-NITRO-2-CHLOROBENZOIC ACID;LABOTEST-BB LT00847209;2-chloro-5-nitro-benzoicaci;6-Chloro-3-nitrobenzoic acid;Benzoic acid, 2-chloro-5-nitro-;2-Chloro-5-nirtrobenzoic acid

   Certification of Analysis

 

 

Item	Specification
Appearance	light yellow crystalline powder
Purity	98.0% min
Moisture	0.5% max
Residue on ignition	0.1% max
Heavy Metal	≤20ppm
Loss on drying	5.0% max

 

                          Function&Application

 

 Used to synthesize 2-chloro-5-aminobenzoic acid, 5-nitrosalicylic acid, ester and amide intermediates.Used as intermediate of pesticide, medicine and organic pigment.

    Product Description

   Certification of Analysis

 

 

Appearance	White to off-white fine powder
L-Leucine Content	46.0~54.0%
L-Isoleucine Content	22.0~27.0%
L-Valine Content	22.0~27.0%
Bulk Density	0.40~0.60g/ml
Particle size	95% through 40mesh
Loss on drying	≤1.0%
Residue on ignition	≤0.40%
Heavy metals	≤10ppm
Arsenic	≤1ppm
Total plate count	≤3000cfu/g
Yeast and Moulds	≤100cfu/g
E.Coli	Negative
Salmonella	Negative/25g
Staphylococcus aureus	Negative/25g

 

                          Function&Application

 Function

Supports extreme muscle growth
Builds strength and tremendous power
Timed release to support anti-catabolic effects
Support increased strength and mass
Support improved recovery and reduced soreness
Promote increased endurance exercise capacity
Provides support against catabolism.

 

Application

1. Skin Care: This product applied on the human skin is with the function of moisturizing, anti-wrinkle, adding nutrition,which is used fr the raw material of high quality mask, moisturizer and cleanser ,can also be used for shampoo and hair care products, bath liquid and so on.
2. Medicines and Health Products :
This product can improve body metabolism, immune function, inhibit cancer cells, activated cells.it has significant function in delaying the human aging, preventing osteoporosis.
3. Food: This product can be added to bread, cakes and various snacks, improve food nutrition structure, especially for children and the elderly digestion and absorption.
4. Dairy products: This product can be widely used in milk drinks, fresh milk, yogurt and other liquid dairy products .have the function of anti-whey precipitation, emulsion stability
5. Beverages:This product can be added to a variety of beverages to make high-energy drinks, play a complementary role in the supplemental energy and body building

    Product Description

Product Name	DL-2-Aminobutyric acid
Synonyms	DL-2-AMINO-N-BUTYRIC ACID; DL-ALPHA-AMINOBUTYRIC ACID
CAS No	2835-81-6
MDL number:	MFCD00008093
EINECS number:	220-616-5
MF	C4H9NO2
MW	103.12
Purity	99%(min)
Moisture	0.5%(max)
Chemical Properties:
Appearence	white to off-white powder
mp	291℃
Safety Information:
Hazard Codes	Xn: Harmful
Risk Statements	20/21/22-36/37/38
Safety Statements	22-24/25-36-26
Usage:	Pharmaceutical Intermediates

 

                          Function&Application

 

 DL-2-Aminobutyric acid is widely used in fields of medicine, food processing, industry, etc.

 

    Product Description

 

   Certification of Analysis

 

 

Item	Specifications	Results
Appearance	Yellow crystals	Yellow crystals
Content%  ≥	99.00	99. 39
Water insolubles  %≤	0.01	0.0037
Cl- % ≤	0. 2	0. 06
sulfate % ≤	0.3	0.10
As  % ≤	0.0001	< 0.0001
Conclusion	The results conforms with Enterprise standards

 

                          Function&Application

 

 Used in the manufacture of pigments, dyeing and oxidizing auxiliaries, paints, inks, red blood salt and potassium, explosives and chemical reagents, also used in steel heat treatment, stone printing, engraving and pharmaceutical industries.Its food additive grade product is mainly used as anti-caking agent of salt.

    Product Description

   Certification of Analysis

 

Item	Specification
Specific rotation	+39.5 to +41.5°
State of solution(transmittance)	Clear 98.0% min.
Chloride[cl]	0.020% max.
Ammonium [NH4]	0.02% max.
Sulfate[SO4]	0.020% max
Iron[Fe]	10ppm max.
Heavy metals [Pb]	10ppm max
Arsenic[As2O3]	1ppm max
Other amino acids	Chromatographically not detectable
Loss on drying	0.20% max.
Residue on ignition[sulfated]	0.10% max.
Assay	99.0% min

 

 

Function&Application

 

It is a key intermediate for the synthesis of anti-aids drugs AZT, DDT and related drugs.

    Product Description

   Certification of Analysis

 

Items	Specifications	Results
Description	A white powder	White powder
Identification	a)      IR: consistent with the spectrum obtained with that of its RS. b)      HPLC: the retention time of the principle peak corresponds to that of its RS. c)       TCL for lactose: position, color and size to the principal spot is consistent with that obtained with reference solution	Conforms   Conforms   Conforms
Nitrates	NMT 0.5%	Conforms
Heavy metals	NMT 10ppm	Conforms
Related substances	Isosorbide: NMT 0.20% Isosorbide 2-nitrate: NMT 0.25% Isosorbide dinitrate: NMT 0.25% Any other single impurity (major): NMT 0.1% Total impurities: NMT 0.5%	Conforms 0.023% 0.041% 0.0026% 0.067%
Microbiological Quality	Total aerobic microbial count: NMT 900cfu/g Total combined yeasts/Molds count: NMT 90 cfu/g Escherichia. Coli: absence	<10cfu/g <10cfu/g absence
Assay (Isosorbide Mononitrate)	66.5%~73.5%	68.5%
Conclusion: conforms to the requirement of USP32 standard.

 

 

Function&Application

Long-term treatment of coronary heart disease, prevention of vasospasm and mixed cardiomyopathy, is also applicable to the treatment after myocardial infarction and long-term treatment of chronic heart failure.