China (Mainland)
Dimethyl sulfoxide CAS NO.67-68-5
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- Dimethyl sulfoxide
- 67-68-5
- Demasorb
Quick Details
- ProName: Dimethyl sulfoxide
- CasNo: 67-68-5
- Molecular Formula: C2H6OS
- Appearance: colourless liquid
- Application: A polar aprotic solvent used in polyme...
- DeliveryTime: 10days
- PackAge: in drums
- Port: Tianjin xingang
- ProductionCapacity: 10 Metric Ton/Day
- Purity: 99%
- Storage: Store at RT.
- Transportation: by sea
- LimitNum: 1 Kilogram
- Heavy metal: less than 0.05%
- Grade: Industrial Grade
- purity: 99
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| Usage | DMSO is a polar aprotic solvent used in chemical reactions, in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines; embryonic stem cells (ESC), and hematopoietic stem cells. DMSO is frequently used in the combinations with BSA or fetal bovine serum (FBS). |
| Usage | Human and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowers |
| Usage | Dimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, DMSO may help improve yields, especially in long PCR. |
| Usage | A polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. |
| Usage | Suitable for HPLC, spectrophotometry, environmental testing |
Details
| Dimethyl sulfoxide Chemical Properties |
| mp | 18.4 °C |
| bp | 189 °C(lit.) |
| density | 1.100 g/mL at 20 °C |
| vapor density | 2.7 (vs air) |
| vapor pressure | 0.42 mm Hg ( 20 °C) |
| FEMA | 3875 |
| refractive index |
n |
| Fp | 192 °F |
| storage temp. | Store at RT. |
| form | liquid (temperature dependent) |
| color | clear colorless |
| FreezingPoint | 18.4℃ |
| Sensitive | Hygroscopic |
| Merck | 14,3259 |
| BRN | 506008 |
| Stability: | Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic. |
| Chemical Properties | It is colorless liquid, and is hygroscopic. It is almost odorless with a bitter taste. It can be dissolved in water, ethanol, acetone, ether, benzene and chloroform. |
| Application |
1. It can be used for the extraction of arene, also as the reaction medium used for resins and dyes, and applied to acrylic polymerization and spinning solvent. 2. It can be used as an organic solvent, reaction medium and the intermediates of organic synthesis. It is highly versatile. This product has a highly selective extraction capacity, and can be used as the polymerization and condensation solvent of acrylic resin and polysulfone resin, as the polymerization and spinning solvent of polyacrylonitrile and cellulose acetate, as the extraction solvent for separating alkanes and arenes, and as the reaction medium for the arenes, butadiene extraction, acrylic fiber, plastic solvents, organic and synthetic dyes, and pharmaceuticals industries. In the field of medicine, dimethyl sulfoxide has anti-inflammatory and analgesic effect with a strong capability of penetration through the skin, and thus being able to dissolve certain drugs and boost their penetration into the human body to achieve the therapeutic purposes. Taking this carrier property of dimethyl sulfoxide can make it be used as pesticide additives. Add a small amount of dimethyl sulfoxide in some pesticides can facilitate the penetration of pesticides into the plant in order to improve the efficacy. dimethyl sulfoxide can also be used as the dye solvent, dye removing agent, and dye carrier for the synthetic fibers. It can also be used as the absorbent of recycling acetylene and sulfur dioxide and also the modifiers of synthetic fiber, antifreeze agent and the capacitor dielectric, brake oil, and extractant of the rare metals. 3. It can be used as analytic solvents and fixing agent of gas chromatography as well as the solvent for analyzing UV spectra. |
| Production method | dimethyl sulfoxide is generally made by using dimethyl sulfide oxidation method. They have different production processes due to the different oxidants and oxidation types. 1. Methanol carbon disulfide method; take carbon disulfide and methanol as raw materials and use γ-Al2O3 as the catalyst; first synthesize the dimethyl sulfide, then have oxidation reaction with nitrogen dioxide (or nitrate) to obtain dimethyl sulfoxide. 2. The hydrogen peroxide method: take acetone as the buffer medium to have dimethyl sulfide be reacted with hydrogen peroxide. This method of dimethyl sulfoxide synthesis has a relative high cost and thus is suitable for large-scale production. 3. The method of nitrogen dioxide: have methanol and hydrogen sulfide dimethyl sulfide reacted in the catalysis of γ- alumina to obtain dimethyl sulfide; have sulfate reacted with sodium nitrite to generate nitrogen dioxide; dimethyl sulfide has gas-liquid phase reaction with nitrogen dioxide at 60-80 °C to produce crude dimethyl sulfoxide. Sometimes people also use oxygen for direct oxidation which also generates the crude dimethyl sulfoxide. Then after vacuum distillation, refine to get the finished product of dimethyl sulfoxide. This method is a relative advanced production method. 4. Dimethyl sulfate method: apply dimethyl sulfate to react with sodium sulfide to obtain dimethyl sulfide; sulfate has reaction with sodium nitrite to generate nitrogen dioxide; dimethyl sulfide is oxidized with nitrogen dioxide to generate the crude dimethyl sulfoxide, and then undergo neutralization and distillation to obtain refined dimethyl sulfoxide product. In addition, the anodic oxidation method can also produce dimethyl sulfoxide via dimethyl sulfide. |
| Chemical Properties | colourless liquid |
| Usage | DMSO is a polar aprotic solvent used in chemical reactions, in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines; embryonic stem cells (ESC), and hematopoietic stem cells. DMSO is frequently used in the combinations with BSA or fetal bovine serum (FBS). |
| Usage | Human and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowers |