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Male hormone drugs |
Testosterone enanthate is male hormone drugs, and testosterone propionate and testosterone heptanoic acid ester compound preparation. The Function is the same as the acetone testosterone, can promote the male organ and secondary development, against the estrogen. And also protein assimilation, can make the muscle growth, weight gain, etc. Its function is quick, and sustained for a long time, injection 250 mg can maintain efficacy for 2~4 weeks. Clinical application to treat male gonads insufficiency, genital dysplasia, infertility, no testosterone deficiency and stabilizing testosterone, etc., it can also be used for women functional uterine bleeding, menopausal syndrome, breast cancer and organ cancer, cirrhosis of the liver, aplastic anemia, osteoporosis, wasting disease.
[side effect] large dose or use for a long time, and can cause water sodium retention and edema. Young women can appear masculine phenomenon, such as thick voice, hairy, acne, clitoral hypertrophy, etc. Prostate cancer, and pregnant women are banned to use. An enlarged prostate and liver and renal function disorder are careful to use heptanoic acid testosterone. When treatment of breast cancer, finding high blood calcium, it should be stopped immediately. |
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Male contraceptive pill |
Testosterone enanthate is a hormone, it can restrain the pituitary gland, promote gonadal hormone release, so that the secretion of leydig cells of endogenous testosterone decline, finally achieve the goal of blocking spermatogenesis. In Institute of zoolocy of Chinese academy of sciences, the test on the monkey found that testosterone enanthate injections 1 times a week, after a week the monkey's sperm cells began to apoptosis, to the fifth week sperm apoptosis up to peak. The clinical trial of 308 volunteers showed that the effect of birth control pills of testosterone enanthate for Asian men is significantly higher than white. In this study, although the decrement of sperm did not present racial differences, but Asian are more sensitive to hormone induced spermatogenesis suppression than white people, more than 95% of the asians can achieve no sperm, and only 40% to 70% of white people become no sperm.
Testosterone enanthate is a kind of long-term male pill, can through a variety of ways to take medicine (2 times per week to once every three weeks, 200 ~ 500 mg each time, intramuscular injection). Through more than 100 cases of volunteers, the results show that the intramuscular injection of 250 mg once week, after 10 weeks, it can make the most of men's sperm have no or less severe sperm, sperm count can be recovered after withdrawal time, adverse reactions with the former. Such as the injection interval extended to more than 10 ~ 12 d, the effect of double dose is not ideal. Pharmacokinetic studies have shown that the product immediately after injection is up to a super physiological levels of blood. Then blood concentration drops rapidly, illustrating the weekly dose necessary. The blood rush may directly stimulate the sperm production, failed to achieve less obvious sperm. Some volunteers can rise again after a few volunteers sperm density decreased. Testosterone enanthate injections 1 times a week, like testosterone propionate. But even so, also it is very difficult for most people to accept. The other two testosterone preparations, namely ring e testosterone propionate and cyclohexane carboxylic acid testosterone, also needed to injection once a week. |
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Chemical property |
White crystalline powder. Melting point is 34-36 ℃. |
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Application |
Clinical application in diseases such as male hypofunction, aplastic anemia, etc. |
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Usage |
Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells. |
China (Mainland)
