CAS 137234-62-9 Voriconazole CAS NO.137234-62-9
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- Product Details
Keywords
- Voriconazole
- 137234-62-9
- Voriconazole supplier
Quick Details
- ProName: CAS 137234-62-9 Voriconazole
- CasNo: 137234-62-9
- Molecular Formula: C16H14F3N5O
- Appearance: powder or crystal
- Application: CAS 137234-62-9 Voriconazole
- DeliveryTime: within 1-2days
- PackAge: Aluminum Foil Bag or as your requirem...
- Port: tianjin
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 99%
- Storage: keep in dry place
- Transportation: as your requirement
- LimitNum: 1 Kilogram
- Grade: Industrial Grade
- MOQ: 1KG
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Product Name: | Voriconazole |
CAS: | 137234-62-9 |
MF: | C16H14F3N5O |
MW: | 349.31 |
EINECS: | 200-261-5 |
Product Categories: | Fine Chemical;antifungal;API;Antifungal (Systemic);Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Heterocycles;Pfizer compounds;Inhibitor;ZINACEF |
Mol File: | 137234-62-9.mol |
Voriconazole is an ergosterol biosynthesis inhibitor, as well as systemic antifungal. This compound, like many antifungal agents, is an inhibitor of CYP2C9, an enzyme involved in the oxidative metabolism of many xenobiotics. Voriconazole is an inhibitor of CYP51A1.
Details
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ItemsSpecificationsResultsAppearanceWhite to off-white powderWhite powderSolubilityFreely soluble in dichloromethane and acetone; soluble in methanol and trichloromethane; slightly soluble in waterCompliesIdentification(1) IRSample IR spectrum corresponds to that of the standardsComplies(2) HPLCThe retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assayCompliesTestTriazole acetophenone: ≤0.12%Not detectedEthyl fluropyrimidine: ≤0.12%0.10%Voriconazole related compound A: ≤0.12%Not detectedRelated substance(RR,SS)6- Chlorovoriconazole: ≤0.12%0.09%6- Chlorovoriconazole: ≤0.12%0.09%Any unspecified impurity: ≤0.1%0.08%Total impurities:≤0.5%0.40%Heavy MetalNMT 10ppm<10ppmResidue on ignitionNMT 0.1%0.06%Enantiomeric purityVoriconazole related compound B: ≤0.12%Not detectedLoss on DryingNMT 0.5%0.04%TrichloromethaneNMT 60ppmNot detectedDichloromethaneNMT 600ppmNot detectedMethanolNMT 3000ppmNot detected2-propanolNMT 5000ppm200ppmAcetoneNMT 5000ppmNot detectedAssay( on dried basis )98.0%~102.0%99.40%ConclusionComplies with the specification
a. It is a triazole antifungal medication, it can cure empirical antifungal therapy.
b. It has become the new standard of care in the treatment of invasive aspergillosis.
c. It can used in the treat of esophageal candidiasis.
d. It has also been used to treat severe fungal corneal infection.
e. An antifungal (systemic). An ergosterol biosynthesis inhibitor.
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Product Name: | Polyethylene-polypropylene glycol |
Synonyms: | BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL;SYNPERONIC F 108;SYNPERONIC L 121;SYNPERONIC L 122;SYNPERONIC P 105;SYNPERONIC P 85;SYNPERONIC PE(R)/F68;SYNPERONIC PE(R)/L61 |
CAS: | 9003-11-6 |
MF: | C5H10O2 |
MW: | 0 |
EINECS: |
618-355-0 |
Product Name: | Lamivudine |
Synonyms: | LaMivudine(Epivir);4-AMino-1-[(2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;3TC (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine;3TC/Epivir-HBV;4-AMino-1-((2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl)pyriMidin-2(1H)-one;LaMivudine-13C-d2;cis-Lamivudine;(-)-BCH-189 |
CAS: | 134678-17-4 |
MF: | C8H11N3O3S |
MW: | 229.26 |
Product Categories: | API;DENDRID;Piperazines;Active Pharmaceutical Ingredients;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Anti-virals;Intermediates & Fine Chemicals;Pharmaceuticals;API's;HIV/AIDS/Related Products;Sulfur & Selenium Compounds |
Mol File: |
134678-17-4.mol |