Anastrozole of API CAS 120511-73-1 CAS NO.120511-73-1
- FOB Price: USD: 1,300.00-1,300.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,
- Available Specifications:
99%(1-2)Kilogram
- Product Details
Keywords
- Anastrozole
- 120511-73-1
- Anastrozole supplier
Quick Details
- ProName: Anastrozole of API CAS 120511-73-1
- CasNo: 120511-73-1
- Molecular Formula: C17H19N5
- Appearance: powder or crystal
- Application: Anastrozole of API CAS 120511-73-1
- DeliveryTime: within 1-2days
- PackAge: Aluminum Foil Bag or as your requirem...
- Port: tianjin
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 99%
- Storage: keep in dry place
- Transportation: as your requirement
- LimitNum: 1 Kilogram
- Grade: Industrial Grade
- MOQ: 1KG
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Anastrozole, sold under the trade name Arimidex among others, is a medication used in addition to other treatments for breast cancer. Specifically it is used for hormone receptor-positive breast cancer. It has also been used to prevent breast cancer in those at high risk. It is taken by mouth
Details
Product Introduction
1.Product name: Anastrozole
2.Synonym: Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile
Assay99%
3.Molecular formulaC17H19N5
4.Molecular weight 293.37
5.Appearancewhite crystal powder
6.CAS number120511-73-1
7.Medicinal categoriesnon-steroidal aromatase inhibitors
Items |
Standard |
Results |
Description |
White crystalline powder |
Complies |
Identification |
IR HPLC Reactive |
Conform with standard IR Conform with standard HPLC Conform |
Solubility |
Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile |
Complies |
Total Impurity |
max.0.5% |
0.18% |
Total Unspecified Impurity |
max. 0.2% |
0.08% |
Individual unspecified impurlty |
max. 0.1% |
0.05% |
Related compound B |
max. 0.2% |
0.07% |
Related compound C |
max. 0.2% |
0.04% |
Related compound D |
max. 0.1% |
0.05% |
Related compound E |
max. 0.1% |
0.06% |
Limit of cyclohexane |
max. 0.08% |
ND |
Limit of ethylacetate |
max. 0.1% |
0.07% |
Melting point |
81.0~84.0°C |
82.5~83.2°C |
Water |
max. 0.3% |
0.21% |
Residue on ignition |
max. 0.1% |
0.07% |
Heavy Metals |
max.0.001% |
Complies |
Assay(HPLC) |
98.0%~102.0% |
99.8% |
Storage |
Cool and dry |
|
Conclusion |
It complies to USP32 . |
Anastrozole is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. The 50% inhibitory concentration (IC50) value of anastrozole to placental aromatase is 15nmol/L.
Anastrozole dosage:
It is very important that you take tablets according to the instructions your doctor or pharmacist gives you. You should take the right dose, not more or less. It is a long term treatment and you usually need to take it for several years. Never stop taking a cancer drug without talking to your specialist first.
If you accidentally take more anastrozole than you should, let your doctor know straight away.
If you forget a dose, continue with the next dose as normal. Don't take an extra dose to make up for the missed one.
Anastrozole Uses:
(2) Its used to cure the breast cancer.
(3) Anastrozole is the third-generation’s aromatase inhibitors, used for the treatment of advanced breast cancer of postmenopausal patients. It is an inhibitor for the triazole aromatase with a strong selectivity. It can inhibits aromatase which is prerequisite for the synthesis of pigment cells P-450 thereby blocking the biosynthesis of estrogens, and the estrogen is the essential part of the growth of breast cancer cells. Its used to cure the breast cancer, particularly suitable for postmenopausal women with advanced breast cancer who recrudescent after hormone adjuvant therapy.
- P Packaging Details
- 25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
- Delivery Time
- Shipped in 3 days after payment
Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 3 days when get the payment.
Shipping :
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英文名称: | N1-BENZYL-N1-ETHYL-PROPANE-1,3-DIAMINE |
英文同义词: | |
CAS号: | 140134-63-0 |
分子式: | C12H20N2 |
分子量: |
192.3 |