SNS-314 Mesylate cas1146618-41-8 CAS NO.1146618-41-8

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Product Details

Keywords

SNS-314
1146618-41-8
SNS-314 Mesylate

Quick Details

ProName: SNS-314 Mesylate cas1146618-41-8
CasNo: 1146618-41-8
Molecular Formula: C21H17NO3S2
Appearance: powder or crystal
Application: SNS-314 Mesylate cas1146618-41-8
DeliveryTime: within 1-2days
PackAge: Aluminum Foil Bag or as your requirem...
Port: tianjin
ProductionCapacity: 1000 Metric Ton/Month
Purity: 99%
Storage: keep in dry place
Transportation: as your requirement
LimitNum: 1 Kilogram
Grade: Industrial Grade
MOQ: 1KG

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SNS-314 is a selective and potent pan Aurora inhibitor currently in a dose escalation phase 1 clinical trial for the treatment of patients with advanced solid tumors. SNS-314 has predominantly additive effects when administered concurrently with commonly used anticancer agents. Sequential administration of SNS-314 with chemotherapeutic compounds showed additive antiproliferative effects with carboplatin, gemcitabine, 5-FU, daunomycin, and SN-38, and synergy was observed in combination with gemcitabine, docetaxel, or vincristine.SNS-314 mesylate is capable to efficiently reduce cell growth and tumorigenicity of different ATC derived cell lines suggesting its potential therapeutic value for ATC treatment.

Name		N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)

Molecular Structure

Molecular Formula		C₁₈H₁₅ClN₆OS₂^.CH₄O₃S
Molecular Weight		527.03
CAS Registry Number		1146618-41-8

Details

Name		N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)

Molecular Structure

Molecular Formula		C₁₈H₁₅ClN₆OS₂^.CH₄O₃S
Molecular Weight		527.03
CAS Registry Number		1146618-41-8

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Package: 1kg/Aluminum foil bag

Production Capacity: 500 Kilogram/Month

Appearance: white powder

Packaging & Shipping

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3-(1H-Imidazol-4-yl)pyridine
[CAS] 51746-85-1
[Synonyms] 3-(1H-IMIDAZOL-4-YL)PYRIDINE 4-(3-PYRIDYL)IMIDAZOLE 3-(1h-imidazol-4-yl)-pyridin 3-(4-Imidazolyl)Pyridine 3-(1H-Imidazol-4-yl)pyridineDiscontinued See: I351751 4-(3-Pyridyl)imidazol
[Molecular Formula] C8H7N3
[MDL Number] MFCD01691712
[Molecular Weight] 145.16

[Appearance] Light Yellow Solid
[mp ] 117-118°C
[Usage] Imidazole rings are found in numberous natural compounds such as enzymes, nucleic acid, and alkaloids that play a role in biological processes

CAS:	451492-95-8
name	MP-412
other name	MP-412;AV-412;AV-412 (free base);N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quin;N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide;N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-2-propenamide;2-PropenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-
name:	AV-412
CBNumber:	CB52500949
mf	C27H28ClFN6O
mw	507.02

Name	AT-9283	EINECS
CAS No. 896466-76-5		Density	1.45g/cm³
Solubility		Melting Point
Formula	C₁₉H₂₃N₇O₂	Boiling Point
Molecular Weight	381.4316	Flash Point
Transport Information		Appearance
Safety		Risk Codes
Molecular Structure		Hazard Symbols
Synonyms

Name	AT-9283	EINECS
CAS No.	896466-76-5	Density	1.45g/cm³
Solubility		Melting Point
Formula	C₁₉H₂₃N₇O₂	Boiling Point
Molecular Weight	381.4316	Flash Point
Transport Information		Appearance
Safety		Risk Codes
Molecular Structure		Hazard Symbols
Synonyms

Product Name:	N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide
Synonyms:	N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide;N-[2-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)aMino]-5-(trifluoroMethyl)-4-pyriMidinyl]aMino]Methyl]phenyl]-N-MethylMethanesulfonaMide;N-methyl-N-(2-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)phenyl)methanesulfonamide;N-Methyl-N-[2-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide PF-431396;N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methyl-Methanesulfonamide hydrate;PF-431396 hydrate;PF 431396, >=98%;N-Methyl-N-(2-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)p
CAS:	717906-29-1
MF:	C22H21F3N6O3S
MW:	506.5